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Total 66104 results found since Jan 2013.

Boy wins £120,000 damages for narcolepsy triggered by swine flu vaccine
Ruling comes after government claimed illness was not serious enough to merit payment, and opens door for up to 100 families to seek compensationA 12-year-old boy has been awarded £120,000 by a court that agreed he had been left severely disabled by narcolepsy triggered by the swine flu vaccine, following a three-year battle in which the government had claimed that his illness was not serious enough to merit payment. The ruling is expected to lead to as many as 100 other families of people affected by the sleeping disorder after receiving the vaccine bringing fresh compensation claims, in a dispute where the governme...
Source: Guardian Unlimited Science - June 10, 2015 Category: Science Authors: Hannah Devlin Science correspondent Tags: UK news Pharmaceuticals industry Drugs Law GlaxoSmithKline Health Science Swine flu Source Type: news

Seven Year-Old Vaccine-Injured Boy Refused Compensation For Not Being Disabled Enough
Conclusion When it comes to compensation, many of the world’s governments shirk their responsibilities and turn a blind eye to suffering families. Families are repeatedly encouraged to apply for compensation even though the governments are fully aware that they will be refused compensation when they do. It is families like the Hadfields who need the money the most. Josh is a child who has clearly been injured after receiving a vaccination recommended by the government and yet his family has been refused compensation because the VDPU has deemed him as not disabled enough. How disabled does a child have to be, for goodness...
Source: vactruth.com - October 11, 2013 Category: Health Medicine and Bioethics Commentators Authors: Christina England Tags: Christina England Top Stories Josh Hadfield Lord Ashley narcolepsy Pandemrix swine flu vaccine injury vaccine injury compensation Source Type: blogs

Viruses, Vol. 13, Pages 1160: African Swine Fever Virus Ubiquitin-Conjugating Enzyme Is an Immunomodulator Targeting NF- κB Activation
Viruses, Vol. 13, Pages 1160: African Swine Fever Virus Ubiquitin-Conjugating Enzyme Is an Immunomodulator Targeting NF-κB Activation Viruses doi: 10.3390/v13061160 Authors: Lucía Barrado-Gil Ana del Puerto Inmaculada Galindo Miguel Ángel Cuesta-Geijo Isabel García-Dorival Carlos Maluquer de Motes Covadonga Alonso African swine fever virus (ASFV) is an acute and persistent swine virus with a high economic burden that encodes multiple genes to evade host immune response. In this work, we have revealed that early viral protein UBCv1, the only known conjugating enzyme encoded by a virus, modulates inna...
Source: Viruses - June 17, 2021 Category: Virology Authors: Luc ía Barrado-Gil Ana del Puerto Inmaculada Galindo Miguel Ángel Cuesta-Geijo Isabel Garc ía-Dorival Carlos Maluquer de Motes Covadonga Alonso Tags: Article Source Type: research

Research Articles CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine
One approach to analgesia is to block pain at the site of origin or along the peripheral pathway by selectively ablating pain-transmitting neurons or nerve terminals directly. The heat/capsaicin receptor (TRPV1) expressed by nociceptive neurons is a compelling target for selective interventional analgesia because it leaves somatosensory and proprioceptive neurons intact. Resiniferatoxin (RTX), like capsaicin, is a TRPV1 agonist but has greater potency. We combine RTX-mediated inactivation with the precision of computed tomography (CT)–guided delivery to ablate peripheral pain fibers in swine. Under CT guidance, RTX w...
Source: Science Translational Medicine - September 16, 2015 Category: Biomedical Science Authors: Brown, J. D., Saeed, M., Do, L., Braz, J., Basbaum, A. I., Iadarola, M. J., Wilson, D. M., Dillon, W. P. Tags: Research Articles Source Type: research

Viruses, Vol. 14, Pages 1593: African Swine Fever Virus Manipulates the Cell Cycle of G0-Infected Cells to Access Cellular Nucleotides
Zaven A. Karalyan African swine fever virus manipulates the cell cycle of infected G0 cells by inducing its progression via unblocking cells from the G0 to S phase and then arresting them in the G2 phase. DNA synthesis in infected alveolar macrophages starts at 10–12 h post infection. DNA synthesis in the nuclei of G0 cells is preceded by the activation of the viral genes K196R, A240L, E165R, F334L, F778R, and R298L involved in the synthesis of nucleotides and the regulation of the cell cycle. The activation of these genes in actively replicating cells begins later and is less pronounced. The subsequent...
Source: Viruses - July 22, 2022 Category: Virology Authors: Hranush R. Avagyan Sona A. Hakobyan Arpine A. Poghosyan Nane V. Bayramyan Hranush H. Arzumanyan Liana O. Abroyan Aida S. Avetisyan Lina A. Hakobyan Elena M. Karalova Zaven A. Karalyan Tags: Article Source Type: research

Evolution of a Search: The Use of Dynamic Twitter Searches During Superstorm Sandy
Conclusion The most important lesson learned from Superstorm Sandy was the need for a dynamic and flexible monitoring process and strategy to understand and respond quickly to health needs in the areas impacted by Superstorm Sandy. Search strategies should change as frequently as the unfolding event. The inability to adapt to a changing situation ensures stale and stagnant terminology and search results. Twitter lists and Boolean searches should be used together to maximize situational awareness. The most important information comes from the impacted population, whether news, local government or local citizens. These are t...
Source: PLOS Currents Disasters - September 26, 2014 Category: Global & Universal Authors: Sara Harris Smith Source Type: research

Effectiveness of job search interventions: A meta-analytic review.
The current meta-analytic review examined the effectiveness of job search interventions in facilitating job search success (i.e., obtaining employment). Major theoretical perspectives on job search interventions, including behavioral learning theory, theory of planned behavior, social cognitive theory, and coping theory, were reviewed and integrated to derive a taxonomy of critical job search intervention components. Summarizing the data from 47 experimentally or quasi-experimentally evaluated job search interventions, we found that the odds of obtaining employment were 2.67 times higher for job seekers participating in jo...
Source: Psychological Bulletin - March 3, 2014 Category: Psychiatry & Psychology Authors: Liu, Songqi; Huang, Jason L.; Wang, Mo Source Type: research

Privacy Still at Risk Despite New CBP Search Rules
International travelers, citizens and foreigners alike, enjoy reduced privacy protections at ports of entry. Thanks to the “border exception” to the Fourth Amendment, Customs and Border Protection (CBP) officers do not need reasonable suspicion or probable cause to search electronic devices at airports. This regrettable authority made headlines last year after CBP officers searched phones belonging to innocent Ameri can citizens. CBP has updated its electronic device search policy via a new directive. While the directive does include a welcome clarification, it states that CBP can search anyone’s electronic devices ...
Source: Cato-at-liberty - January 8, 2018 Category: American Health Authors: Matthew Feeney Source Type: blogs

Eye Tracking Measures Reveal How Changes in the Design of Displays for Augmentative and Alternative Communication Influence Visual Search in Individuals With Down Syndrome or Autism Spectrum Disorder.
Conclusions Small changes to the organization of the simulated augmentative and alternative communication display resulted in substantial differences in eye gaze and speed to find a target. Of greatest clinical import is the finding that clustering symbols reduced attention to distracters, given that individuals with disabilities may be prone to distraction. PMID: 31398294 [PubMed - as supplied by publisher]
Source: American Journal of Speech-Language Pathology - August 9, 2019 Category: Speech-Language Pathology Authors: Wilkinson KM, Madel M Tags: Am J Speech Lang Pathol Source Type: research

A search strategy to identify studies on the prognosis of work disability: a diagnostic test framework
Conclusions The Work Disability Prognosis filter will help practitioners and researchers who want to find prognostic evidence in the area of work disability evaluation. However, further refining of this filter is possible and needed, especially for the practitioner for whom efficiency is especially important.
Source: BMJ Open - May 19, 2015 Category: Journals (General) Authors: Kok, R., Verbeek, J. A. H. M., Faber, B., van Dijk, F. J. H., Hoving, J. L. Tags: Open access, Epidemiology, Evidence based practice, Occupational and environmental medicine, Public health Research Source Type: research

Project SEARCH UK – Evaluating Its Employment Outcomes
ConclusionProject SEARCH UK represents a valuable addition to the supported employment provision in the UK. Its unique model should inform discussions around best practice in supported employment. Implications for other supported employment programmes are discussed.
Source: Journal of Applied Research in Intellectual Disabilities - September 1, 2015 Category: Disability Authors: Axel Kaehne Tags: Original Article Source Type: research

A Solution in Search of a Problem
Last week, Georgia Governor Nathan Deal’s Education Reform Commission released its draft recommendations for improving and expanding the state’s school choice programs. While some of the commission’s proposed changes are meritorious, the commission failed to recommend expanding the state’s highly popular, nearly universal scholarship tax credit (STC), instead proposing that the state create a new STC that is highly regulated and much more limited in scope. The commission’s two proposed changes to the existing STC (having the Department of Revenue count actual contributions against the tax credit cap rather than m...
Source: Cato-at-liberty - September 25, 2015 Category: American Health Authors: Jason Bedrick Source Type: blogs

IJERPH, Vol. 20, Pages 6036: Unemployment and Job Search Behavior among People with Disabilities during the First Year of the COVID-19 Pandemic in Germany
rer Not much is known about how the COVID-19 pandemic affected the labor market experiences of people with disabilities. Since they constitute a generally disadvantaged group in the labor market, it is important to scrutinize whether their position has worsened during these difficult times and how they reacted with regard to their job search behavior. We therefore used data for the year 2020 from a large German panel (Panel Arbeitsmarkt und Soziale Sicherung, PASS), in order to scrutinize the prevalence of unemployment among people with disabilities (N = 739) during the first year of the COVID-19 pandemic. The factors ...
Source: International Journal of Environmental Research and Public Health - June 2, 2023 Category: Environmental Health Authors: Karsten Ingmar Paul Alfons Hollederer Tags: Article Source Type: research

Identifying people with a learning disability: an advanced search for general practice.
CONCLUSION: The Read Code search supported practices to populate their registers and was quick to run and review, making it a viable choice to support register revalidation. However, it did not find large numbers of people eligible for the LD register who were previously unidentified by their practice, suggesting that additional complementary methods are required to support practices to validate their registers. PMID: 29061717 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - October 23, 2017 Category: Primary Care Authors: Russell AM, Bryant L, House A Tags: Br J Gen Pract Source Type: research

IJERPH, Vol. 12, Pages 5815-5832: In Search of an Integrative Measure of Functioning
International trends towards people-centred, integrative care and support require any measurement of functioning and disability to meet multiple aims. The information requirements of two major Australian programs for disability and rehabilitation are outlined, and the findings of two searches for suitable measures of functioning and disability are analysed. Over 30 current measures of functioning were evaluated in each search. Neither search found a generic measure of functioning suitable for these multibillion dollar programs, relevant to a wide range of people with a variety of health conditions and functioning experienc...
Source: International Journal of Environmental Research and Public Health - May 26, 2015 Category: Environmental Health Authors: Rosamond MaddenNick GlozierNicola FortuneMaree DysonJohn GilroyAnita BundyGwynnyth LlewellynLuis Salvador-CarullaSue LukersmithElias MpofuRichard Madden Tags: Article Source Type: research